/ Dictionary / Index D defusion: Meaning and Definition of Find definitions for: de•fu•sion Pronunciation: (dē-fy'zhun), [key] — n. Psychoanal. separation of the life instinct from the death instinct, a process often accompanying maturity. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. defuse defuze Related Content Daily Word Quiz: nonchalant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language