/ Dictionary / Index D depressant: Meaning and Definition of Find definitions for: de•pres•sant Pronunciation: (di-pres'unt), [key] — adj. having the quality of depressing or lowering the vital activities; sedative. causing a lowering in spirits; dejecting. causing a drop in value; economically depressing. —n. a sedative. Cf. stimulant (def. 1). any agent capable of diminishing a specific property of a substance. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: depressant (Thesaurus) depress depressed Related Content Daily Word Quiz: impetuous Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language