/ Dictionary / Index D despond: Meaning and Definition of Find definitions for: de•spond Pronunciation: (di-spond' or, esp. for 2, des'pond), [key] — v.i. to be depressed by loss of hope, confidence, or courage. —n. despondency. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: despond (Thesaurus) despoliation despondency Related Content Daily Word Quiz: belligerent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language