/ Dictionary / Index D despondency: Meaning and Definition of Find definitions for: de•spond•en•cy Pronunciation: (di-spon'dun-sē), [key] — n. state of being despondent; depression of spirits from loss of courage or hope; dejection. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: despondency (Thesaurus) despond despondent Related Content Daily Word Quiz: soporific Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language