/ Dictionary / Index F frameshift: Meaning and Definition of Find definitions for: frame•shift Pronunciation: (frām'shift"), [key] — n. Genetics. the addition or deletion of one or more nucleotides in a strand of DNA, which shifts the codon triplets of the genetic code of messenger RNA and causes a misreading during translation, resulting in an aberrant protein and therefore a mutation. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. framepack frame-up Related Content Daily Word Quiz: censure Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language