/ Dictionary / Index H holocrine: Meaning and Definition of Find definitions for: hol•o•crine Pronunciation: (hol'u-krin, -krīn", hō'lu-), [key] — adj. (of a gland) releasing a secretion that is a product of disintegrating cells. (of a secretion) released by such a gland. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Holocene holoenzyme Related Content Daily Word Quiz: serendipity Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language