/ Dictionary / Index H holoenzyme: Meaning and Definition of Find definitions for: hol•o•en•zyme Pronunciation: (hol"ō-en'zīm), [key] — n. an enzyme complete in both its apoenzyme and coenzyme components. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. holocrine Holofernes Related Content Daily Word Quiz: simian Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language