/ Dictionary / Index I irritant: Meaning and Definition of Find definitions for: ir•ri•tant Pronunciation: (ir'i-tnt), [key] — adj. tending to cause irritation; irritating. —n. anything that irritates. a biological, chemical, or physical agent that stimulates a characteristic function or elicits a response, esp. an inflammatory response. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: irritant (Thesaurus) irritable heart irritate Related Content Daily Word Quiz: penury Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language