/ Dictionary / Index I irritate: Meaning and Definition of Find definitions for: ir•ri•tate Pronunciation: (ir'i-tāt"), [key] — v., -tat•ed, -tat•ing. —v.t. to excite to impatience or anger; annoy. to excite (a living system) to some characteristic action or function. to bring (a body part) to an abnormally excited or sensitive condition. —v.i. to cause irritation or become irritated. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: irritate (Thesaurus) irritant irritated Related Content Daily Word Quiz: sequester Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language