/ Dictionary / Index M man-to-man: Meaning and Definition of Find definitions for: man-to-man Pronunciation: (man'tu-man'), [key] — adj. characterized by directness, openness, etc.; frank and personal: He had a man-to-man talk with his son about sex. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: man-to-man (Thesaurus) mantling man-to-man defense Related Content Daily Word Quiz: philtrum Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language