/ Dictionary / Index M man-to-man defense: Meaning and Definition of Find definitions for: man'-to-man' defense' Pronunciation: [key] a method of defense in team sports, esp. in basketball and football, in which each member of the defensive team is designated to guard a particular member of the offensive team. Cf. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. man-to-man Mantoux test Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language