/ Dictionary / Index M Middlesborough: Meaning and Definition of Find definitions for: Mid•dles•bor•ough Pronunciation: (mid'lz-bûr"ō, -bur"ō), [key] — n. a city in SE Kentucky. 12,251. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Middle River Middlesbrough Related Content Daily Word Quiz: gregarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language