/ Dictionary / Index M Middlesbrough: Meaning and Definition of Find definitions for: Mid•dles•brough Pronunciation: (mid'lz-bru), [key] — n. a seaport in NE England, on the Tees estuary. 153,300. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Middlesborough middlescence Related Content Daily Word Quiz: gregarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language