/ Dictionary / Index O opuscule: Meaning and Definition of Find definitions for: o•pus•cule Pronunciation: (ō-pus'kyl), [key] — n. a small or minor work. a literary or musical work of small size. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. opus opusculum Related Content Daily Word Quiz: vertigo Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language