/ Dictionary / Index P pick-off: Meaning and Definition of Find definitions for: pick-off Pronunciation: (pik'ôf", -of"), [key] — n. a play in which a base runner, caught off base, is tagged out by an infielder on a quick throw, usually from the pitcher or catcher. a mechanism that senses mechanical motion and produces a corresponding electric signal. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: pick-off (Thesaurus) pick-me-up pickpocket Related Content Daily Word Quiz: hale Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language