/ Dictionary / Index P prefrontal: Meaning and Definition of Find definitions for: pre•fron•tal Pronunciation: (prē-frun'tl), [key] — adj. Anat. anterior to, situated in, or pertaining to the anterior part of a frontal structure. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: prefrontal (Thesaurus) preformation prefrontal lobotomy Related Content Daily Word Quiz: simian Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language