/ Dictionary / Index S Sistine: Meaning and Definition of Find definitions for: Sis•tine Pronunciation: (sis'tēn, -tin, -tīn), [key] — adj. of or pertaining to any pope named Sixtus. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Sister of Mercy Sistine Chapel Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language