/ Dictionary / Index S sistrum: Meaning and Definition of Find definitions for: sis•trum Pronunciation: (sis'trum), [key] — pl. -trums, -tra an ancient Egyptian percussion instrument consisting of a looped metal frame set in a handle and fitted with loose crossbars that rattle when shaken. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Sistine Madonna* Sisyphean Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language