/ Dictionary / Index S spleno-: Meaning and Definition of Find definitions for: spleno- Pronunciation: [key] a combining form representingin compound words: splenomegaly. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. splenius splenomegaly Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language