/ Dictionary / Index U Upjohn: Meaning and Definition of Find definitions for: Up•john Pronunciation: (up'jon"), [key] 1802–78, and his son,1828–1903, U.S. architects, born in England. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: upjohn (Thesaurus) Upington upkeep Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language