Columbia Encyclopedia

Search results

293 results found

colchicine

(Encyclopedia)colchicine kŏlˈchəsēnˌ [key], alkaloid extracted from plants of the genus Colchicum and especially from the corms of the autumn crocus, Colchicum autumnale (see meadow saffron). The metabolic eff...

Rothman, James Edward

(Encyclopedia)Rothman, James Edward, 1950–, American cell physiologist, b. Haverhill, Mass., Ph.D. Harvard, 1976. Rothman was a professor at Stanford from 1978 to 1988 and at Princeton from 1988 to 1991. He taugh...

saccharin

(Encyclopedia)saccharin săkˈərĭn [key], C7H5NSO3, white, crystalline, aromatic compound. It was discovered accidentally by I. Remsen and C. Fahlberg in 1879. Pure saccharin tastes several hundred times as sweet...

thalidomide

(Encyclopedia)thalidomide thəlĭdˈəmĭdˌ [key], sleep-inducing drug found to produce skeletal defects in developing fetuses. The drug was marketed in Europe, especially in West Germany and Britain, from 1957 to...

Ratcliffe, Sir Peter John

(Encyclopedia)Ratcliffe, Sir Peter John, 1954–, British cellular and molecular biologist, M.D., Cambridge, 1987. He has been a researcher at Oxford since 1987. Ratcliffe, along with William Kaelin and Gregg Semen...

Paganini, Niccolò

(Encyclopedia)Paganini, Niccolò nēkōlōˈ pägänēˈnē [key], 1782–1840, Italian violinist, whose virtuosity became a legend. He extended the compass of the violin by his use of harmonics, perfected the use ...

nitrogen mustard

(Encyclopedia)nitrogen mustard, any of various poisonous compounds originally developed for military use (see poison gas). Like mustard gas and lewisite, it is a vesicant (blistering agent). In the form of its crys...

Ohsumi, Yoshinori

(Encyclopedia)Ohsumi, Yoshinori, 1945–, Japanese biologist, Ph.D. Univ. of Tokyo, 1974. He was a researcher at the Univ. of Tokyo from 1977 to 1996, when he joined the National Institute for Basic Biology in Japa...

Benacerraf, Baruj

(Encyclopedia)Benacerraf, Baruj bäˈro͞okh bĕnăsˈərəf [key], 1920–2011, American immunologist, b. Caracas, Venezuela, grad. Columbia (B.S., 1942), Medical College of Virginia (M.D., 1945). Raised in Paris,...

spinal puncture

(Encyclopedia)spinal puncture, surgical penetration of the spinal canal by a hollow needle introduced between two of the lumbar vertebrae. The arrangement permits injection of antibiotics or anesthetics (see anesth...