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Weller, Thomas Huckle

(Encyclopedia)Weller, Thomas Huckle, 1915–2008, American microbiologist and physician, b. Ann Arbor, Mich., B.A. Univ. of Michigan, 1936, M.D. Harvard, 1940. In 1936 he began teaching at Harvard, and as a special...

infection

(Encyclopedia)infection, invasion of plant or animal tissues by microorganisms, i.e., bacteria, viruses, viroids, fungi, rickettsias, and protozoans. The invasion of body tissues by parasitic worms and other higher...

Gajdusek, Daniel Carleton

(Encyclopedia)Gajdusek, Daniel Carleton gīdˈəshĕkˌ [key], 1923–2008, American virologist, b. Yonkers, N.Y., grad. Univ. of Rochester; M.D. Harvard, 1945. He worked in the United States, Iran, Australia, and ...

Smithies, Oliver

(Encyclopedia)Smithies, Oliver, 1925–2017, American geneticist, b. Halifax, England, Ph.D., Oxford, 1951. Smithies was on the faculty at the Univ. of Toronto (1953–60) and Univ. of Wisconsin–Madison (1960–8...

Ramazzini, Bernardino

(Encyclopedia)Ramazzini, Bernardino bārnärdēˈnō rämät-tsēˈnē [key], 1633–1717, Italian physician. He was professor at Modena (1682–1700) and at Padua until 1714. He is often called the father of indus...

collagen

(Encyclopedia)collagen kŏlˈəjən [key], any of a group of proteins found in skin, ligaments, tendons, bone and cartilage, and other connective tissue. Cells called fibroblasts form the various fibers in connecti...

Crofton, Sir John Wenman

(Encyclopedia)Crofton, Sir John Wenman, 1912–2009, British physician, b. Dublin. He served in the British medical corps during World War II and during 1946–52 was part of a research team studying the effects of...

Charcot, Jean Martin

(Encyclopedia)Charcot, Jean Martin zhäN märtăNˈ shärkōˈ [key], 1825–93, French neurologist. At the Salpêtrière in Paris he developed the greatest clinic of his time for diseases of the nervous system. He...

intoxication

(Encyclopedia)intoxication, condition of body tissue affected by a poisonous substance. Poisonous materials, or toxins, are to be found in heavy metals such as lead and mercury, in drugs, in chemicals such as alcoh...

orphan drug

(Encyclopedia)orphan drug, drug developed under the U.S. Orphan Drug Act (1983) to treat a disease that affects fewer than 200,000 people in the United States. The orphan drug law offers tax breaks and a seven-year...