/ Thesaurus / S Synonyms of self destruct Find synonyms for: Verb1. self-destruct, self-destroy, destroy, destructusage: do away with oneself or itself; "The machine will self-destruct if you tamper with it"WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved. Related Content Daily Word Quiz: pundit Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language